Sunday, April 7, 2013

Intestinal Metabolism of L-CarnitinePromotes Atherosclerosis

This study found that in mice, intestinal bacteria metabolize l-carnitine, producing trimethylamine-N-oxide (TMAO). TMAO promotes atherosclerosis. L-carnitine is a common component of red meat. The authors hypothesize that this metabolism by intestinal bacteria of l-carnitine to TMAO may be responsible for the increased cardiovascular risk associated with the consumption of red meat.