Suicide risk in adolescents with chronic illness: implications for primary care and specialty pediatric practice: a review.
Dev Med Child Neurol. 2010 Aug 31;
Authors: Greydanus D, Patel D, Pratt H
Suicide in adolescents is a global tragedy. Research-identified correlates of suicide in youth include depression, academic failure, loss of friends, social isolation, and substance abuse, among others. This review focuses on the potential link between chronic illness in adolescents and increased suicide risk. Research suggests that chronic illness is a risk factor for depression in adolescents that may induce suicide ideation and attempts; however, this risk may be increased even more in young adulthood if the underlying causes of depression are not resolved. This risk needs to be considered against the research data noting an increase in suicide attempts and completions, in each decade of life from adolescence into adulthood. Although more research is clearly needed, it can be concluded that suicide risks are seen in adolescents with chronic illness and all of these young people should be screened for depression and other risk factors for suicide on a regular basis.
20813018
– Suicide risk in adolescents with chronic illness: implications for primary care and specialty pediatric practice: a review.
Suicide risk in adolescents with chronic illness: implications for primary care and specialty pediatric practice: a review.
Dev Med Child Neurol. 2010 Aug 31;
Authors: Greydanus D, Patel D, Pratt H
Suicide in adolescents is a global tragedy. Research-identified correlates of suicide in youth include depression, academic failure, loss of friends, social isolation, and substance abuse, among others. This review focuses on the potential link between chronic illness in adolescents and increased suicide risk. Research suggests that chronic illness is a risk factor for depression in adolescents that may induce suicide ideation and attempts; however, this risk may be increased even more in young adulthood if the underlying causes of depression are not resolved. This risk needs to be considered against the research data noting an increase in suicide attempts and completions, in each decade of life from adolescence into adulthood. Although more research is clearly needed, it can be concluded that suicide risks are seen in adolescents with chronic illness and all of these young people should be screened for depression and other risk factors for suicide on a regular basis.
20813018
– Suicide risk in adolescents with chronic illness: implications for primary care and specialty pediatric practice: a review.
Comparative effectiveness studies of medications.
Curr Opin Investig Drugs. 2010 Sep;11(9):987-8
Authors: Lane DM
Comparative effectiveness studies of medications or, more appropriately, studies comparing the safety and efficacy of drugs have been conducted for decades, particularly for cancer chemotherapy. Research oncologists can stratify individuals participating in studies using prognostic criteria based on tissue diagnosis and disease staging. Conversely, research cardiologists, in particular those evaluating drugs for atherosclerotic vascular disease, have had to stratify individuals using criteria based on the risk of having a vascular event (ie, coronary heart disease risk). During the past 20 years, new imaging techniques, such as coronary calcium scoring, that are able to screen asymptomatic populations for atherosclerosis have been developed. In the future, studies comparing drugs for cardiovascular disease should be based on the presence of disease, such as atherosclerosis, rather than on the risk of a vascular event.
20730692
– Comparative effectiveness studies of medications.
